HCID 59054439, compound → HCID 59053464, compound

HRID 1400273Notes

Reaction equation

HRID 1400273 reaction equation
[Cl:1][C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[CH:5]=[CH:4][C:3]=1[S:12]([CH2:15][CH2:16][NH:17][CH2:18][C:19]1O[CH:21]=[CH:22][CH:23]=1)(=[O:14])=[O:13].ClC1C2C(=CC=CC=2)C=CC=1SC[CH2:37][NH:38]CC1N(C)C=CC=1>>[Cl:1][C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[CH:5]=[CH:4][C:3]=1[S:12]([CH2:15][CH2:16][NH:17][CH2:18][C:19]1[N:38]([CH3:37])[CH:21]=[CH:22][CH:23]=1)(=[O:14])=[O:13]

Participants

3

Reactant 2

HCID 59054439HCID 59054439, compoundHCID 68151732HCID 68151732, compound

Product 1

HCID 59053464HCID 59053464, compoundYield 76%

Procedure

Prepared as described for compound 25 from 2-[(1-chloronaphthalen-2-yl)sulfanyl]-N-[(1-methyl-1H-pyrrol-2-yl)methyl]ethanamine and in 76% yield as yellow oil.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-2fe636dde4634fb099fa2fd2d93fd91e
Source dataset
uspto-grants-2014_12
Patent number
US08906946B2

Reaction notes

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