2-Thiophenecarboxaldehyde, 5-chloro- → HCID 59053468, compound

HRID 1400278Notes

Reaction equation

HRID 1400278 reaction equation
[Cl:1][C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[CH:5]=[CH:4][C:3]=1[CH2:12][CH2:13][CH2:14][NH2:15].[Cl:16][C:17]1[S:21][C:20]([CH:22]=O)=[CH:19][CH:18]=1>>[Cl:1][C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[CH:5]=[CH:4][C:3]=1[CH2:12][CH2:13][CH2:14][NH:15][CH2:22][C:20]1[S:21][C:17]([Cl:16])=[CH:18][CH:19]=1

Participants

3

Reactant 2

HCID 817002-Thiophenecarboxaldehyde, 5-chloro-HCID 68151387HCID 68151387, compound

Product 1

HCID 59053468HCID 59053468, compoundYield 78%

Procedure

Prepared from 3-(1-chloronaphthalen-2-yl)propan-1-amine and 5-chlorothiophen-2-carbaldehyde in 78% yield as a red oil.

Sources & evidence

ORD record
ord-429a17488b7f4f08b97f183549aa09a6
Source dataset
uspto-grants-2014_12
Patent number
US08906946B2

Reaction notes

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