2-Thiophenecarboxaldehyde → HCID 59053526, compound

HRID 1400279Notes

Reaction equation

HRID 1400279 reaction equation
[Cl:1][C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[CH:5]=[CH:4][C:3]=1[CH2:12][CH2:13][CH2:14][NH2:15].[S:16]1[CH:20]=[CH:19][CH:18]=[C:17]1[CH:21]=O>>[Cl:1][C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[CH:5]=[CH:4][C:3]=1[CH2:12][CH2:13][CH2:14][NH:15][CH2:21][C:17]1[S:16][CH:20]=[CH:19][CH:18]=1

Participants

3

Reactant 2

HCID 73642-ThiophenecarboxaldehydeHCID 68151387HCID 68151387, compound

Product 1

HCID 59053526HCID 59053526, compoundYield 70%

Procedure

Prepared from 3-(1-chloronaphthalen-2-yl)propan-1-amine and thiophen-2-carbaldehyde in 70% yield as a slightly red oil.

Sources & evidence

ORD record
ord-cb0a18db0e704cd5a32e5f90cef89746
Source dataset
uspto-grants-2014_12
Patent number
US08906946B2

Reaction notes

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