2-Thiophenecarboxaldehyde → HCID 59053657, compound

HRID 1400297Notes

Reaction equation

HRID 1400297 reaction equation
[Cl-].[F:2][C:3]1[C:12]2[C:7](=[CH:8][CH:9]=[CH:10][CH:11]=2)[CH:6]=[CH:5][C:4]=1[O:13][CH2:14][CH2:15][NH3+:16].[S:17]1[CH:21]=[CH:20][CH:19]=[C:18]1[CH:22]=O>>[F:2][C:3]1[C:12]2[C:7](=[CH:8][CH:9]=[CH:10][CH:11]=2)[CH:6]=[CH:5][C:4]=1[O:13][CH2:14][CH2:15][NH:16][CH2:22][C:18]1[S:17][CH:21]=[CH:20][CH:19]=1

Participants

3

Reactant 2

HCID 73642-ThiophenecarboxaldehydeHCID 68151396HCID 68151396, compound

Product 1

HCID 59053657HCID 59053657, compoundYield 82%

Procedure

Prepared from 2-[(1-fluoronaphthalen-2-yl)oxy]ethanaminium chloride and thiophen-2-carbaldehyde in 82% yield as a white oil.

Sources & evidence

ORD record
ord-fcf47897a2b8493880ac6fd85626982f
Source dataset
uspto-grants-2014_12
Patent number
US08906946B2

Reaction notes

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