HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1400302Generated: November 1, 2026
Tert-butyl {2-[(1-chloro-6-cyanonaphthalen-2-yl)oxy]ethyl}carbamate → 2-[(1-Chloro-6-cyanonaphthalen-2-yl)oxy]ethanaminium chloride
https://huagongshe.com/reaction/1400302
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Tert-butyl {2-[(1-chloro-6-cyanonaphthalen-2-yl)oxy]ethyl}carbamate | HCID 86709755 | — |
| Solvent | Hydrochloric Acid | HCID 313 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | 2-[(1-Chloro-6-cyanonaphthalen-2-yl)oxy]ethanaminium chloride | HCID 68151287 | 95% |
Reaction Steps
To a cooled (0° C.) single necked flask containing a solution of tert-butyl {2-[(1-chloro-6-cyanonaphthalen-2-yl)oxy]ethyl}carbamate in 3 mL of ethyl ether, 5 mL of 4 M HCl solution in dioxane were added. The resulting mixture was stirred at room temperature overnight. The solution was concentrated under reduce pressure to afford 2-[(1-chloro-6-cyanonaphthalen-2-yl)oxy]ethanaminium chloride as a white solid (95% yield).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US08906946B2 |
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| Source dataset | uspto-grants-2014_12 |
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| ORD ID | ord-7d2651051a34422ea6a3ba1e24275a06 |
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| Source note | uspto-grants-2014_12 |
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