HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Thiophenecarboxaldehyde → 5-Chloro-6-{2-[(thiophen-2-ylmethyl)amino]ethoxy}naphthalene-2-carbonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Thiophenecarboxaldehyde | HCID 7364 | — |
| Reactant | 2-[(1-Chloro-6-cyanonaphthalen-2-yl)oxy]ethanaminium chloride | HCID 68151287 | — |
| Product | 5-Chloro-6-{2-[(thiophen-2-ylmethyl)amino]ethoxy}naphthalene-2-carbonitrile | HCID 59053720 | 35% |
Reaction Steps
Prepared from 2-[(1-chloro-6-cyanonaphthalen-2-yl)oxy]ethanaminium chloride and thiophen-2-carbaldehyde in 35% yield as a whitish solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08906946B2 |
| Source dataset | uspto-grants-2014_12 |
| ORD ID | ord-6ccf748f58ad4eb1a8d56ff3dc499022 |
| Source note | uspto-grants-2014_12 |