反应详情

A solution of 1-(4-fluorophenyl)ethanone (1 equiv.) in DMSO is added to the reaction mixture dropwise over 20 min. and stirred at RT for 4 h. The reaction is monitored by TLC and at completion the reaction mixture is poured in water (100 mL) and extracted with EtOAc. The combined organic extract is washed with water, followed by brine, dried over sodium sulfate and evaporated to dryness.

1. extractionextracted with EtOAc
2. extractionThe combined organic extract
3. washis washed with water
4. dry with materialdried over sodium sulfate
5. customevaporated to dryness