HCID 86710756, compound → HCID 86710755, compound

Participants

Reaction Steps

A solution of methyl (2S)-2-(tert-butoxy)-2-[32-fluoro-4-methyl-29-oxa-5,7,8,26-tetraazaheptacyclo[24.6.2.16,9.110,14.02,7.015,20.030,34]hexatriaconta-1 (32),2,4,6(36),8,10(35),11,13,15 (20),16,18,23,30,33-tetradecaen-3-yl]acetate (0.023 g, 0.036 mmol) in MeOH (5 mL) was treated with 10 wt % Pd/C (4 mg, 0.04 mmol), evacuated and hydrogen back-filled three times, then stirred under hydrogen atmosphere for 18 h. The crude mixture was filtered (0.45 μm syringe tip filter) and the filtrate solution was used immediately in the following step. LCMS (M+H)=649.5.

Provenance & Evidence