HCID 86710767, compound → HCID 86710766, compound

Participants

Reaction Steps

A solution of methyl (2S)-2-(tert-butoxy)-2-[4-methyl-29-oxa-5,7,8-triazaheptacyclo[24.6.2.16,9. 110,14.02,7.015,20.030,34]hexatriaconta-1(32),2,4,6(36),8,10(35),11,13,15 (20),16,18,23,30,33-tetradecaen-3-yl]acetate (0.051 g, 0.082 mmol) in MeOH (5 mL) was treated with 10 wt % Pd/C (9 mg, 0.08 mmol), then evacuated and hydrogen gas filled three times. The reaction was stirred for 16 h. The reaction mixture was filtered (0.45 nm syringe tip filter) and the filtrate solution was used directly in the following step. LCMS (M+H)=630.5.

Provenance & Evidence