HCID 67442531, compound → HCID 67448275, compound

Participants

Reaction Steps

A solution of 17 (1.21 g, mixture of 17 and 18) in toluene (50 mL) was heated to reflux for 1 h then cooled to RT. The reaction mixture was then concentrated, re-dissolved in MeOH, and concentrated again. The residue was triturated with a mixture of AcOEt/hexanes. The resulting suspension (gel) was collected by filtration, rinsed with hexanes, air-dried and dried under high vacuum to afford the title compound 18 (1.157 g, 1.74 mmol, quant, yield) as an off-white solid. MS (m/z): 665.6 (M+H).

Provenance & Evidence