HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phenylacetonitrile → 2-Formyl-2-phenylacetonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phenylacetonitrile | HCID 8794 | — |
| Reactant | Ethyl orthoformate | HCID 31214 | — |
| Reactant | 4-Phenyl-1H-pyrazol-5-amine | HCID 79703 | — |
| Product | 2-Formyl-2-phenylacetonitrile | HCID 345880 | — |
Reaction Steps
4-Aryl-3-aminopyrazoles such as 4-phenyl-2H-pyrazol-3-ylamine may be prepared according to the procedures described in patent EP269,859 and illustrated in the following scheme, by reacting benzeneacetonitrile with orthoformic acid triethyl ester to give 3-oxo-2-phenyl-propionitrile which is reacted with hydrazine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08907092B2 |
| Source dataset | uspto-grants-2014_12 |
| ORD ID | ord-d50e9a3748464592ac4114595e62c667 |
| Source note | uspto-grants-2014_12 |