反应详情

温度

40 °C

1-benzyl-4-phenyl-1H-1,2,3-triazole (0.52 g, 2.197 mmol) prepared above and iodomethane (2 ml, 32.0 mmol) were added to a 20 mL vial. The reaction was heated at 40° C. for 3 days. The iodomethane was allowed to evaporate in the hood. The crude product was dissolved with 2 mL CH2Cl2 under reflux. The solution was precipitated into a mixture of acetone, ethyl acetate and hexane. The yellow solid was collected and dried in vacuo.

1. additionwere added to a 20 mL vial
2. customto evaporate in the hood
3. dissolutionThe crude product was dissolved with 2 mL CH2Cl2
4. temperatureunder reflux
5. customThe solution was precipitated into a mixture of acetone, ethyl acetate and hexane
6. customThe yellow solid was collected
7. customdried in vacuo