Methyl iodide → HCID 178496246, compound

HRID 1401368Notes

Reaction equation

HRID 1401368 reaction equation
[CH3:1][O:2][CH2:3][CH2:4][O:5][CH2:6][CH2:7][O:8][CH2:9][CH2:10][N:11]1[CH:15]=[C:14]([C:16]2[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=2)[N:13]=[N:12]1.[I:22][CH3:23]>C(#N)C>[I-:22].[CH3:1][O:2][CH2:3][CH2:4][O:5][CH2:6][CH2:7][O:8][CH2:9][CH2:10][N:11]1[CH:15]=[C:14]([C:16]2[CH:17]=[CH:18][CH:19]=[CH:20][CH:21]=2)[N+:13]([CH3:23])=[N:12]1

Participants

4

Reactant 2

HCID 6328Methyl iodideHCID 1177228851-(2-(2-(2-methoxyethoxy)ethoxy)ethyl)-4-phenyl-1H-1,2,3-triazole

Product 1

HCID 178496246HCID 178496246, compound

Reagents, catalysts & solvents 1

HCID 6342AcetonitrileSolvent

Procedure

The 1-(2-(2-(2-methoxyethoxy)ethoxy)ethyl)-4-phenyl-1H-1,2,3-triazole was refluxed with excess iodomethane in acetonitrile for more than 12 hours and concentrated after cooling to room temperature. The product was rinsed with organic solvent, recrystallized with ethyl acetate and dried in vacuo. The following 1-(2-(2-(2-methoxyethoxy)ethoxy)ethyl)-3-methyl-4-phenyl-1H-1,2,3-triazol-3-ium iodide structure was confirmed:

Workup

  1. concentrationconcentrated
  2. washThe product was rinsed with organic solvent
  3. customrecrystallized with ethyl acetate
  4. customdried in vacuo

Sources & evidence

ORD record
ord-124db89e5fc74b809924f57628b5b5c5
Source dataset
uspto-grants-2014_12
Patent number
US08907105B1

Reaction notes

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