1-Methyl-1H-indole-3-carbaldehyde → HCID 89500615, compound

HRID 1401730Notes

Reaction equation

[CH3:1][C:2]1[CH:7]=[CH:6][C:5]2[O:8][CH2:9][C:10]([CH2:12][O:13][C:4]=2[CH:3]=1)=[O:11].[CH3:14][N:15]1[C:23]2[C:18](=[CH:19][CH:20]=[CH:21][CH:22]=2)[C:17]([CH:24]=O)=[CH:16]1>>[CH3:1][C:2]1[CH:7]=[CH:6][C:5]2[O:8]/[C:9](=[CH:24]\[C:17]3[C:18]4[C:23](=[CH:22][CH:21]=[CH:20][CH:19]=4)[N:15]([CH3:14])[CH:16]=3)/[C:10](=[O:11])/[C:12](=[CH:24]/[C:17]3[C:18]4[C:23](=[CH:22][CH:21]=[CH:20][CH:19]=4)[N:15]([CH3:14])[CH:16]=3)/[O:13][C:4]=2[CH:3]=1

Participants

Reactant 2

HCID 878941-Methyl-1H-indole-3-carbaldehyde

HCID 120101Methyl benzodioxepinone

Product 1

HCID 89500615HCID 89500615, compound

Procedure

Calone is reacted with 1-methylindole-3-carbaldehyde analogously to the reaction conditions of Example 1, giving 7-methyl-2,4-bis[1-(1-methyl-1H-indol-3-yl)meth-(Z)-ylidene]benzo[b]-1,4-dioxepin-3-one.

Sources & evidence

ORD record: ord-149f592a1cf84e5094a902c9d7ebd638
Source dataset: uspto-grants-2014_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08907110B2

Reaction notes

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