HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-((Tert-butyldimethylsilyl)oxy)acetaldehyde → HCID 67347933, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-((Tert-butyldimethylsilyl)oxy)acetaldehyde | HCID 4187788 | — |
| Reactant | HCID 67323525 | HCID 67323525 | — |
| Reactant | HCID 86671824 | HCID 86671824 | — |
| Product | HCID 67347933 | HCID 67347933 | — |
Reaction Steps
The preparation is carried out starting from 1-[4-(1,1-dimethylindan-5-yl)thiazol-2-yl]piperidin-4-ylamine hydrochloride and (tert-butyldimethylsilanyloxy)acetaldehyde. The protecting group is cleaved off as already described by means of a 1M tetramethylammonium/THF solution. The product was purified by means of preparative HPLC and converted into the hydrochloride.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08907098B2 |
| Source dataset | uspto-grants-2014_12 |
| ORD ID | ord-2b13bee4f2174476ae1826021f33a43f |
| Source note | uspto-grants-2014_12 |