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HRID1401768

反应详情

EQUATION

反应方程式

HRID 1401768 的结构方程式

REACTANTS

反应物

3
结构：CC(C)(C)[Si](C)(C)OCC=O
HCID4187788

(tert-Butyldimethylsilyloxy)acetaldehyde

C8H18O2Si

结构：C1CCOC1.CCCC[N+](CCCC)(CCCC)CCCC.[F-]
HCID11078149

未命名化合物

结构：Br.CC1(C)CCC(C)(C)c2cc(-c3csc(N4CCC(N)CC4)n3)ccc21
HCID68380909

未命名化合物

PRODUCTS

生成物

1
结构：CC1(C)CCC(C)(C)c2cc(-c3csc(N4CCC(N(CCO)CCO)CC4)n3)ccc21
HCID68304963

未命名化合物

PROCEDURE

实验过程

The preparation is carried out starting from 1-[4-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)thiazol-2-yl]piperidin-4-ylamine hydrobromide and (tertbutyldimethylsilanyloxy)acetaldehyde. The protecting group is cleaved off as already described by means of a 1M TBAF/THF solution. The product was purified by means of reversed-phase chromatography and converted into the hydrochloride.

WORKUP

后处理

  1. customThe product was purified by means of reversed-phase chromatography