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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1401769Generated: October 30, 2026

2-((Tert-butyldimethylsilyl)oxy)acetaldehyde → HCID 53311190, compound

https://huagongshe.com/reaction/1401769

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-((Tert-butyldimethylsilyl)oxy)acetaldehydeHCID 4187788—
ReactantHCID 53312203HCID 53312203—
ReactantHCID 86671824HCID 86671824—
ProductHCID 53311190HCID 53311190—

Reaction Steps

The preparation is carried out starting from 1-[4-(5,5-dimethyl-5,6,7,8-tetrahydronaphthalen-2-yl)thiazol-2-yl]piperidin-4-ylamine and (tert-butyldimethylsilanyloxy)acetaldehyde. The protecting group is cleaved off as already described by means of a 1M tetramethylammonium/THF solution. The product was purified by means of preparative HPLC and converted into the hydrochloride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08907098B2
Source datasetuspto-grants-2014_12
ORD IDord-3628ddae1dab4b21a27d8a9848407e3f
Source noteuspto-grants-2014_12