5-Hydroxypentanal → HCID 53311544, compound

HRID 1401794Notes

Reaction equation

Cl.[CH3:2][C:3]1([CH3:26])[CH2:12][CH2:11][C:10]([CH3:14])([CH3:13])[C:9]2[CH:8]=[C:7]([C:15]3[N:19]=[C:18]([N:20]4[CH2:25][CH2:24][NH:23][CH2:22][CH2:21]4)[S:17][N:16]=3)[CH:6]=[CH:5][C:4]1=2.[OH:27][CH2:28][CH2:29][CH2:30][CH2:31][CH:32]=O>>[CH3:2][C:3]1([CH3:26])[CH2:12][CH2:11][C:10]([CH3:13])([CH3:14])[C:9]2[CH:8]=[C:7]([C:15]3[N:19]=[C:18]([N:20]4[CH2:21][CH2:22][N:23]([CH2:32][CH2:31][CH2:30][CH2:29][CH2:28][OH:27])[CH2:24][CH2:25]4)[S:17][N:16]=3)[CH:6]=[CH:5][C:4]1=2

Participants

Reactant 2

HCID 202055-Hydroxypentanal

HCID 68381307HCID 68381307, compound

Product 1

HCID 53311544HCID 53311544, compound

Procedure

The preparation was carried out as already described starting from 65 mg (0.17 mmol) of 1-[3-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)-1,2,4-thiadiazol-5-yl]piperazine hydrochloride and 17 mg (0.165 mmol) of 5-hydroxypentanal.

Sources & evidence

ORD record: ord-23168a39cce64efb95e595f4706da062
Source dataset: uspto-grants-2014_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08907098B2

Reaction notes

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