HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 67323558, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | 3-(2-Chloroethyl)-1,3-oxazolidin-2-one | HCID 75633 | — |
| Reactant | HCID 67166643 | HCID 67166643 | — |
| Product | HCID 67323558 | HCID 67323558 | — |
Reaction Steps
The preparation was carried out as already described starting from 100 mg (0.26 mmol) of 4-[4-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)thiazol-2-yl]piperidine hydrochloride and 46 mg (0.31 mmol) of 3-(2-chloroethyl)oxazolidin-2-one. The protecting group was cleaved off using a 1N sodium hydroxide solution. The product is in the form of the hydrochloride.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08907098B2 |
| Source dataset | uspto-grants-2014_12 |
| ORD ID | ord-2941fcb5f87a401fac8abc92ce3546d6 |
| Source note | uspto-grants-2014_12 |