5-Hydroxypentanal → HCID 68381042, compound

Participants

Reaction Steps

The preparation was carried out as already described via a reductive amination starting from 70 mg (0.20 mmol) of 4-[2-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)thiazol-5-yl]piperidine and 40 mg (0.40 mmol) of 5-hydroxypentanal. The product was purified by means of preparative HPLC and converted into the hydrochloride by treatment with methanolic HCl.

Provenance & Evidence