HuagongsheHuagongshe Chemistry Print Report · For research reference only
Chloromethyl ethyl ether → (NE)-5-chloro-N-[1-(ethoxymethyl)pyrimidin-4-ylidene]-2,4-difluorobenzenesulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Chloromethyl ethyl ether | HCID 18523 | — |
| Reactant | 5-chloro-2,4-difluoro-N-pyrimidin-4-ylbenzenesulfonamide | HCID 59436545 | — |
| Product | (NE)-5-chloro-N-[1-(ethoxymethyl)pyrimidin-4-ylidene]-2,4-difluorobenzenesulfonamide | HCID 59436509 | — |
Reaction Steps
Prepared according to the process of Preparation 716 using 5-chloro-2,4-difluoro-N-pyrimidin-4-ylbenzenesulfonamide, Preparation 723 and chloromethyl ethyl ether. The product was a mixture of three regioisomers that were not separated and used in subsequent reactions as a mixture.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08907101B2 |
| Source dataset | uspto-grants-2014_12 |
| ORD ID | ord-912fda730e534e429d6b522d906bd5ed |
| Source note | uspto-grants-2014_12 |