HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,4,5-Trifluorobenzenesulfonyl chloride → tert-Butyl 1,3-thiazol-4-yl[(2,4,5-trifluorophenyl)sulfonyl]carbamate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,4,5-Trifluorobenzenesulfonyl chloride | HCID 2776979 | — |
| Reactant | tert-butyl N-(1,3-thiazol-4-yl)carbamate | HCID 53241636 | — |
| Product | tert-Butyl 1,3-thiazol-4-yl[(2,4,5-trifluorophenyl)sulfonyl]carbamate | HCID 59436528 | — |
Reaction Steps
The above titled compound was prepared from 2,4,5-trifluorobenzenesulfonyl chloride (5.0 g, 0.022 mol) and thiazole-4-yl-carbamic acid tert-butyl ester (Preparation 72, 4.3 g, 0.022 mol) using the method of Preparation 453 to afford the product as a white solid (6.84 g, 80%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08907101B2 |
| Source dataset | uspto-grants-2014_12 |
| ORD ID | ord-bf4b5ce23a5847c893fca61760bd975c |
| Source note | uspto-grants-2014_12 |