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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 140261Generated: October 28, 2026

Phosphorus oxychloride → Methyl 6-chloro-2-(2,4-difluorophenylamino)-5-fluoronicotinate

https://huagongshe.com/reaction/140261

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPhosphorus oxychlorideHCID 24813—
ReactantPhosphorus pentachlorideHCID 24819—
ReactantMethyl 2-(2,4-difluorophenylamino)-5-fluoro-6-hydroxynicotinateHCID 178498343—
ProductMethyl 6-chloro-2-(2,4-difluorophenylamino)-5-fluoronicotinateHCID 13849310—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (9/10)
ORD IDord-0b13a4c33bc84503b3f54a145be2b355
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (9/10)