4-(4-Chlorophenyl)dihydro-2H-pyran-2,6(3H)-dione → HCID 45380984, compound

HRID 1402785Notes

Reaction equation

HRID 1402785 reaction equation
[NH2:1][C:2]1[CH:3]=[C:4]([CH:7]=[CH:8][C:9]=1[NH2:10])[C:5]#[N:6].[Cl:11][C:12]1[CH:17]=[CH:16][C:15]([CH:18]2[CH2:24][C:23](=O)[O:22][C:20](=[O:21])[CH2:19]2)=[CH:14][CH:13]=1>>[Cl:11][C:12]1[CH:13]=[CH:14][C:15]([CH:18]([CH2:24][C:23]2[NH:1][C:2]3[CH:3]=[C:4]([C:5]#[N:6])[CH:7]=[CH:8][C:9]=3[N:10]=2)[CH2:19][C:20]([OH:22])=[O:21])=[CH:16][CH:17]=1.[ClH:11]

Participants

3

Reactant 2

HCID 1046394-(4-Chlorophenyl)dihydro-2H-pyran-2,6(3H)-dioneHCID 7372853,4-Diaminobenzonitrile

Product 1

HCID 45380984HCID 45380984, compound

Procedure

By a procedure similar to that of example 1.4, starting from commercial 3,4-diaminobenzonitrile and 3-(4-chlorophenyl)glutaric anhydride, 3-(4-chlorophenyl)-4-(5-cyano-2-benzimidazolyl)-butanoic acid•HCl was obtained as light beige solid.

Sources & evidence

ORD record
ord-c7ac4332774a46c5ada34e0eac395fd6
Source dataset
uspto-grants-2014_12
Patent number
US08912186B2

Reaction notes

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