4-(4-Chlorophenyl)dihydro-2H-pyran-2,6(3H)-dione → HCID 45380986, compound

HRID 1402787Notes

Reaction equation

HRID 1402787 reaction equation
[NH2:1][C:2]1[CH:3]=[C:4]([CH:9]=[CH:10][C:11]=1[NH2:12])[C:5]([O:7]C)=[O:6].[Cl:13][C:14]1[CH:19]=[CH:18][C:17]([CH:20]2[CH2:26][C:25](=O)[O:24][C:22](=[O:23])[CH2:21]2)=[CH:16][CH:15]=1>>[C:5]([C:4]1[CH:9]=[CH:10][C:11]2[N:12]=[C:25]([CH2:26][CH:20]([C:17]3[CH:16]=[CH:15][C:14]([Cl:13])=[CH:19][CH:18]=3)[CH2:21][C:22]([OH:24])=[O:23])[NH:1][C:2]=2[CH:3]=1)([OH:7])=[O:6].[ClH:13]

Participants

3

Reactant 2

HCID 1046394-(4-Chlorophenyl)dihydro-2H-pyran-2,6(3H)-dioneHCID 1355243,5-Diamino-2-methylbenzoic acid

Product 1

HCID 45380986HCID 45380986, compound

Procedure

By a procedure similar to that of example 1.4, starting from methyl 3,4-diaminobenzoate and 3-(4-chlorophenyl)glutaric anhydride, 4-(5-carboxy-2-benzimidazolyl)-3-(4-chlorophenyl)butanoic acid•HCl was obtained as colourless solid.

Sources & evidence

ORD record
ord-5d410e611e264daaa2e2989b8beabfcb
Source dataset
uspto-grants-2014_12
Patent number
US08912186B2

Reaction notes

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