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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1402790Generated: November 1, 2026

4-(4-chlorophenyl)dihydro-2H-pyran-2,6(3H)-dione → HCID 54758208, compound

https://huagongshe.com/reaction/1402790

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(4-chlorophenyl)dihydro-2H-pyran-2,6(3H)-dioneHCID 104639—
Reactant3,5-Diamino-2-methylbenzoic acidHCID 135524—
ProductHCID 54758208HCID 54758208—

Reaction Steps

By a procedure similar to that of example 1.4, starting from methyl 3,4-diaminobenzoate and 3-(4-chlorophenyl)glutaric anhydride, 3-(4-chlorophenyl)-4-(5-methoxycarbonyl-2-benzimidazolyl)-butanoic acid•HCl was obtained as light tan solid, provided that cyclisation of the crude glutaramic acid was carried out in commercial 4M HCl in 1,4-dioxane at reflux for 0.5 h.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08912186B2
Source datasetuspto-grants-2014_12
ORD IDord-dabf688d51514b0d9befad35dbe33581
Source noteuspto-grants-2014_12