4-Iodobenzene-1,2-diamine → HCID 45381202, compound

HRID 1402810Notes

Reaction equation

HRID 1402810 reaction equation
[I:1][C:2]1[CH:7]=[CH:6][C:5]([NH2:8])=[C:4]([NH2:9])[CH:3]=1.[Cl:10][C:11]1[CH:12]=[C:13]([CH:17]2[CH2:23][C:22](=O)[O:21][C:19](=[O:20])[CH2:18]2)[CH:14]=[CH:15][CH:16]=1>>[Cl:10][C:11]1[CH:12]=[C:13]([CH:17]([CH2:23][C:22]2[NH:9][C:4]3[CH:3]=[C:2]([I:1])[CH:7]=[CH:6][C:5]=3[N:8]=2)[CH2:18][C:19]([OH:21])=[O:20])[CH:14]=[CH:15][CH:16]=1.[ClH:10]

Participants

3

Reactant 2

HCID 112070494-Iodobenzene-1,2-diamineHCID 54758299HCID 54758299, compound

Product 1

HCID 45381202HCID 45381202, compound

Procedure

By a procedure similar to that of example 1.4, starting from 4-iodo-1,2-phenylenediamine and 3-(3-chlorophenyl)glutaric anhydride, 3-(3-chlorophenyl)-4-(5-iodo-2-benzimidazolyl)butanoic acid•HCl was obtained as light beige solid.

Sources & evidence

ORD record
ord-38e88f47fd284ca6bc16cc67727fe550
Source dataset
uspto-grants-2014_12
Patent number
US08912186B2

Reaction notes

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