4-Iodobenzene-1,2-diamine → HCID 45381198, compound

HRID 1402811Notes

Reaction equation

HRID 1402811 reaction equation
[I:1][C:2]1[CH:7]=[CH:6][C:5]([NH2:8])=[C:4]([NH2:9])[CH:3]=1.[Cl:10][C:11]1[CH:12]=[C:13]([CH:18]2[CH2:24][C:23](=O)[O:22][C:20](=[O:21])[CH2:19]2)[CH:14]=[CH:15][C:16]=1[Cl:17]>>[Cl:10][C:11]1[CH:12]=[C:13]([CH:18]([CH2:24][C:23]2[NH:9][C:4]3[CH:3]=[C:2]([I:1])[CH:7]=[CH:6][C:5]=3[N:8]=2)[CH2:19][C:20]([OH:22])=[O:21])[CH:14]=[CH:15][C:16]=1[Cl:17].[ClH:10]

Participants

3

Reactant 2

HCID 112070494-Iodobenzene-1,2-diamineHCID 543639424-(3,4-Dichlorophenyl)oxane-2,6-dione

Product 1

HCID 45381198HCID 45381198, compound

Procedure

By a procedure similar to that of example 1.4, starting from 4-iodo-1,2-phenylenediamine and 3-(3,4-dichlorophenyl)glutaric anhydride, 3-(3,4-dichlorophenyl)-4-(5-iodo-2-benzimidazolyl)butanoic acid•HCl was obtained as off-white solid.

Sources & evidence

ORD record
ord-71c59e77168c44db84dbf925d715de11
Source dataset
uspto-grants-2014_12
Patent number
US08912186B2

Reaction notes

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