Hydrochloric Acid → 1H-Benzimidazol-2-amine, 5-chloro-

Participants

Reaction Steps

Commercial 2-aminobenzimidazole was chlorinated with a mixture of hydrogen peroxide and HCl in aqueous solution at rt for 1.5 h. After removal of all volatiles the residue was dissolved in water and the product precipitated by addition of ammonia solution to give a 72% yield of 2-amino-5-chlorobenzimidazole as beige coloured solid.

Provenance & Evidence