Diethyl Malonate → HCID 66759220, compound

Participants

Reaction Steps

To a solution of 1-(4-chlorophenyl)-3-phenylprop-2-en-1-one (1 g) in toluene (10 ml) magnesium oxide (0.41 g) and diethyl malonate (0.62 ml) were added. The slurry was stirred at rt for 2 h. The inorganics were removed by suction filtration and washed with dichloromethane. The filtrate was concentrated in vacuo and the residue was recrystallised from diethyl ether/hexanes to provide diethyl 2-[3-(4-chlorophenyl)-3-oxo-1-phenylpropyl]malonate (1.5 g) as colourless solid.

Provenance & Evidence