3-(4-CHLOROPHENYL)-4'-METHOXYPROPIOPHENONE → HCID 131732159, compound

HRID 1402882Notes

Reaction equation

HRID 1402882 reaction equation
ClC1C=CC(CCC(C2C=CC(OC)=CC=2)=O)=CC=1.[Cl:20][C:21]1[CH:26]=[CH:25][C:24]([CH2:27][CH2:28]/[C:29](/[C:36]2[CH:41]=[CH:40][C:39]([O:42][CH3:43])=[CH:38][CH:37]=2)=[CH:30]/[C:31]([O:33][CH2:34][CH3:35])=[O:32])=[CH:23][CH:22]=1>>[Cl:20][C:21]1[CH:26]=[CH:25][C:24]([CH2:27][CH2:28]/[C:29](/[C:36]2[CH:37]=[CH:38][C:39]([O:42][CH3:43])=[CH:40][CH:41]=2)=[CH:30]\[C:31]([O:33][CH2:34][CH3:35])=[O:32])=[CH:23][CH:22]=1

Participants

3

Reactant 2

HCID 70158653-(4-CHLOROPHENYL)-4'-METHOXYPROPIOPHENONEHCID 131732160HCID 131732160, compound

Product 1

HCID 131732159HCID 131732159, compound

Procedure

By a procedure similar to that of example 1.85.3, starting from 3-(4-chlorophenyl)-1-(4-methoxyphenyl)-propan-1-one, (Z)-ethyl 5-(4-chlorophenyl)-3-(4-methoxyphenyl)pent-2-enoate and (E)-ethyl 5-(4-chlorophenyl)-3-(4-methoxyphenyl)pent-2-enoate were obtained as colourless oils.

Sources & evidence

ORD record
ord-a0a434dc250e4a0f90fb09eda831eed8
Source dataset
uspto-grants-2014_12
Patent number
US08912186B2

Reaction notes

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