Acetophenone → 3-(4-Fluorophenyl)-1-phenylprop-2-en-1-one

HRID 1402886Notes

Reaction equation

HRID 1402886 reaction equation
[F:1][C:2]1[CH:9]=[CH:8][C:5]([CH:6]=O)=[CH:4][CH:3]=1.[C:10]([C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1)(=[O:12])[CH3:11]>>[F:1][C:2]1[CH:9]=[CH:8][C:5]([CH:6]=[CH:11][C:10]([C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=2)=[O:12])=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 7410AcetophenoneHCID 680234-Fluorobenzaldehyde

Product 1

HCID 982013-(4-Fluorophenyl)-1-phenylprop-2-en-1-one

Procedure

By a procedure similar to that of example 1.59.1, starting from 4-fluorobenzaldehyde and acetophenone, 3-(4-fluorophenyl)-1-phenylprop-2-en-1-one was obtained as yellow solid.

Sources & evidence

ORD record
ord-8c038439bd98465fbd614f4027fa51e0
Source dataset
uspto-grants-2014_12
Patent number
US08912186B2

Reaction notes

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