Acetophenone → HCID 4345671, compound
Reaction equation
[F:1][C:2]([F:12])([F:11])[C:3]1[CH:10]=[CH:9][C:6]([CH:7]=O)=[CH:5][CH:4]=1.[C:13]([C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1)(=[O:15])[CH3:14]>>[C:16]1([C:13](=[O:15])[CH:14]=[CH:7][C:6]2[CH:9]=[CH:10][C:3]([C:2]([F:12])([F:11])[F:1])=[CH:4][CH:5]=2)[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1Participants
3
Procedure
By a procedure similar to that of example 1.59.1, starting from 4-trifluoromethylbenzaldehyde and acetophenone, 1-phenyl-3-[4-(trifluoromethyl)phenyl]prop-2-en-1-one was obtained as yellow solid.
Sources & evidence
- ORD record
- ord-53412c41f43946868426cd4643275178
- Source dataset
- uspto-grants-2014_12
- Patent number
- US08912186B2
Reaction notes
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