1-Phenyl-3-[4-(trifluoromethyl)phenyl]propan-1-one → HCID 44220693, compound

HRID 1402893Notes

Reaction equation

HRID 1402893 reaction equation
C1(C(=O)CCC2C=CC(C(F)(F)F)=CC=2)C=CC=CC=1.[C:21]1(/[C:27](/[CH2:34][CH2:35][C:36]2[CH:41]=[CH:40][C:39]([C:42]([F:45])([F:44])[F:43])=[CH:38][CH:37]=2)=[CH:28]\[C:29]([O:31][CH2:32][CH3:33])=[O:30])[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1>>[C:21]1(/[C:27](/[CH2:34][CH2:35][C:36]2[CH:41]=[CH:40][C:39]([C:42]([F:43])([F:44])[F:45])=[CH:38][CH:37]=2)=[CH:28]/[C:29]([O:31][CH2:32][CH3:33])=[O:30])[CH:22]=[CH:23][CH:24]=[CH:25][CH:26]=1

Participants

3

Reactant 2

HCID 157575211-Phenyl-3-[4-(trifluoromethyl)phenyl]propan-1-oneHCID 44222815HCID 44222815, compound

Product 1

HCID 44220693HCID 44220693, compound

Procedure

By a procedure similar to that of example 1.85.3, starting from 1-phenyl-3-[4-(trifluoromethyl)phenyl]-propan-1-one, (Z)-ethyl 3-phenyl-5-[4-(trifluoromethyl)phenyl]pent-2-enoate and (E)-ethyl 3-phenyl-5-[4-(trifluoromethyl)phenyl]pent-2-enoate were obtained as colourless oils.

Sources & evidence

ORD record
ord-d831b5ca30be44068cd2221e5b72466d
Source dataset
uspto-grants-2014_12
Patent number
US08912186B2

Reaction notes

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