Acetophenone → HCID 66759503, compound
Reaction equation
[Cl:1][C:2]1[CH:9]=[CH:8][C:5]([CH:6]=O)=[CH:4][C:3]=1[F:10].[C:11]([C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1)(=[O:13])[CH3:12]>>[Cl:1][C:2]1[CH:9]=[CH:8][C:5]([CH:6]=[CH:12][C:11]([C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)=[O:13])=[CH:4][C:3]=1[F:10]Participants
3
Procedure
By a procedure similar to that of example 1.59.1, starting from 4-chloro-3-fluorobenzaldehyde and acetophenone, 3-(4-chloro-3-fluorophenyl)-1-phenylprop-2-en-1-one was obtained as yellow solid.
Sources & evidence
- ORD record
- ord-54715586714a49359f36c418e4b75ec6
- Source dataset
- uspto-grants-2014_12
- Patent number
- US08912186B2
Reaction notes
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