Acetophenone → HCID 66759642, compound
Reaction equation
[Br:1][C:2]1[CH:9]=[CH:8][C:5]([CH:6]=O)=[C:4]([F:10])[CH:3]=1.[C:11]([C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1)(=[O:13])[CH3:12]>>[Br:1][C:2]1[CH:9]=[CH:8][C:5]([CH:6]=[CH:12][C:11]([C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)=[O:13])=[C:4]([F:10])[CH:3]=1Participants
3
Procedure
By a procedure similar to that of example 1.59.1, starting from 4-bromo-2-fluorobenzaldehyde and acetophenone, 3-(4-bromo-2-fluorophenyl)-1-phenylprop-2-en-1-one was obtained as yellow solid.
Sources & evidence
- ORD record
- ord-9f3d65043c6e4ac7b11ef4cfacfebd37
- Source dataset
- uspto-grants-2014_12
- Patent number
- US08912186B2
Reaction notes
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