HCID 66759880, compound → HCID 131732165, compound

HRID 1402909Notes

Reaction equation

HRID 1402909 reaction equation
ClC1C=CC(C(=O)CCC2C=CC3C(=CC=CC=3)C=2)=CC=1.[Cl:22][C:23]1[CH:28]=[CH:27][C:26]([CH2:29][CH2:30]/[C:31](/[C:38]2[CH:47]=[CH:46][C:45]3[C:40](=[CH:41][CH:42]=[CH:43][CH:44]=3)[CH:39]=2)=[CH:32]/[C:33]([O:35][CH2:36][CH3:37])=[O:34])=[CH:25][CH:24]=1>>[Cl:22][C:23]1[CH:24]=[CH:25][C:26]([CH2:29][CH2:30]/[C:31](/[C:38]2[CH:47]=[CH:46][C:45]3[C:40](=[CH:41][CH:42]=[CH:43][CH:44]=3)[CH:39]=2)=[CH:32]\[C:33]([O:35][CH2:36][CH3:37])=[O:34])=[CH:27][CH:28]=1

Participants

3

Reactant 2

HCID 66759880HCID 66759880, compoundHCID 131732166HCID 131732166, compound

Product 1

HCID 131732165HCID 131732165, compound

Procedure

By a procedure similar to that of example 1.85.3, starting from 1-(4-chlorophenyl)-3-(2-naphthalenyl)propan-1-one, (Z)-ethyl 5-(4-chlorophenyl)-3-(2-naphthalenyl)pent-2-enoate and (E)-ethyl 5-(4-chlorophenyl)-3-(2-naphthalenyl)pent-2-enoate were obtained as colourless oils.

Sources & evidence

ORD record
ord-459e6af081f94935ae64a770d0159a53
Source dataset
uspto-grants-2014_12
Patent number
US08912186B2

Reaction notes

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