HCID 66759088, compound → HCID 131732167, compound

HRID 1402911Notes

Reaction equation

HRID 1402911 reaction equation
ClC1C=CC(C(=O)CCC2C3C(=CC=CC=3)C=CC=2)=CC=1.[Cl:22][C:23]1[CH:28]=[CH:27][C:26]([CH2:29][CH2:30]/[C:31](/[C:38]2[C:47]3[C:42](=[CH:43][CH:44]=[CH:45][CH:46]=3)[CH:41]=[CH:40][CH:39]=2)=[CH:32]/[C:33]([O:35][CH2:36][CH3:37])=[O:34])=[CH:25][CH:24]=1>>[Cl:22][C:23]1[CH:24]=[CH:25][C:26]([CH2:29][CH2:30]/[C:31](/[C:38]2[C:47]3[C:42](=[CH:43][CH:44]=[CH:45][CH:46]=3)[CH:41]=[CH:40][CH:39]=2)=[CH:32]\[C:33]([O:35][CH2:36][CH3:37])=[O:34])=[CH:27][CH:28]=1

Participants

3

Reactant 2

HCID 66759088HCID 66759088, compoundHCID 131732168HCID 131732168, compound

Product 1

HCID 131732167HCID 131732167, compound

Procedure

By a procedure similar to that of example 1.85.3, starting from 1-(4-chlorophenyl)-3-(1-naphthalenyl)propan-1-one, (Z)-ethyl 5-(4-chlorophenyl)-3-(1-naphthalenyl)pent-2-enoate and (E)-ethyl 5-(4-chlorophenyl)-3-(1-naphthalenyl)pent-2-enoate were obtained as colourless oils.

Sources & evidence

ORD record
ord-cb45e099da2642a7a0aa579d26a5c7f6
Source dataset
uspto-grants-2014_12
Patent number
US08912186B2

Reaction notes

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