HCID 21622308, compound → HCID 131732169, compound

HRID 1402915Notes

Reaction equation

HRID 1402915 reaction equation
ClC1C=CC(CCC(C2C=CC=CN=2)=O)=CC=1.[Cl:18][C:19]1[CH:24]=[CH:23][C:22]([CH2:25][CH2:26]/[C:27](/[C:34]2[CH:39]=[CH:38][CH:37]=[CH:36][N:35]=2)=[CH:28]/[C:29]([O:31][CH2:32][CH3:33])=[O:30])=[CH:21][CH:20]=1>>[Cl:18][C:19]1[CH:20]=[CH:21][C:22]([CH2:25][CH2:26]/[C:27](/[C:34]2[CH:39]=[CH:38][CH:37]=[CH:36][N:35]=2)=[CH:28]\[C:29]([O:31][CH2:32][CH3:33])=[O:30])=[CH:23][CH:24]=1

Participants

3

Reactant 2

HCID 21622308HCID 21622308, compoundHCID 131732170HCID 131732170, compound

Product 1

HCID 131732169HCID 131732169, compound

Procedure

By a procedure similar to that of example 1.85.3, starting from 3-(4-chlorophenyl)-1-(2-pyridinyl)propan-1-one, (Z)-ethyl 5-(4-chlorophenyl)-3-(2-pyridinyl)pent-2-enoate and (E)-ethyl 5-(4-chlorophenyl)-3-(2-pyridinyl)pent-2-enoate were obtained as colourless oils.

Sources & evidence

ORD record
ord-f59a1770bf134d24b185e626dab8f944
Source dataset
uspto-grants-2014_12
Patent number
US08912186B2

Reaction notes

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