HCID 44220289, compound → HCID 45272741, compound

HRID 1402921Notes

Reaction equation

HRID 1402921 reaction equation
[Cl:1][C:2]1[CH:3]=[CH:4][C:5]2[O:9][C:8](/[C:10](/[C:17]3[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=3)=[CH:11]\[C:12]([O:14]CC)=[O:13])=[CH:7][C:6]=2[CH:23]=1.ClC1C=CC2OC(/C(/C3C=CC=CC=3)=C/C(OCC)=O)=CC=2C=1.ClC1C=CC2OC(/C(/C3C=CC=CC=3)=C\C(O)=O)=CC=2C=1>>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]2[O:9][C:8](/[C:10](/[C:17]3[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=3)=[CH:11]/[C:12]([OH:14])=[O:13])=[CH:7][C:6]=2[CH:23]=1

Participants

4

Reactant 3

HCID 44220289HCID 44220289, compoundHCID 44222632HCID 44222632, compoundHCID 86662459HCID 86662459, compound

Product 1

HCID 45272741HCID 45272741, compound

Procedure

By a procedure similar to that of example 1.85.4, starting from a mixture of (Z)-ethyl 3-(5-chloro-2-benzofuranyl)-3-phenylacrylate and (E)-ethyl 3-(5-chloro-2-benzofuranyl)-3-phenylacrylate, a mixture of (Z)-3-(5-chloro-2-benzofuranyl)-3-phenylacrylic acid and (E)-3-(5-chloro-2-benzofuranyl)-3-phenylacrylic acid was obtained as yellowish solid.

Sources & evidence

ORD record
ord-44bb639c8baa43d7982de6c938d6ad6a
Source dataset
uspto-grants-2014_12
Patent number
US08912186B2

Reaction notes

Loading…