HCID 44220288, compound → HCID 44220287, compound

HRID 1402925Notes

Reaction equation

HRID 1402925 reaction equation
C(C1SC2C=CC(Cl)=CC=2C=1)(=O)C1C=CC=CC=1.[Cl:19][C:20]1[CH:21]=[CH:22][C:23]2[S:27][C:26](/[C:28](/[C:35]3[CH:40]=[CH:39][CH:38]=[CH:37][CH:36]=3)=[CH:29]\[C:30]([O:32][CH2:33][CH3:34])=[O:31])=[CH:25][C:24]=2[CH:41]=1>>[Cl:19][C:20]1[CH:21]=[CH:22][C:23]2[S:27][C:26](/[C:28](/[C:35]3[CH:40]=[CH:39][CH:38]=[CH:37][CH:36]=3)=[CH:29]/[C:30]([O:32][CH2:33][CH3:34])=[O:31])=[CH:25][C:24]=2[CH:41]=1

Participants

3

Reactant 2

HCID 44220288HCID 44220288, compoundHCID 44222634HCID 44222634, compound

Product 1

HCID 44220287HCID 44220287, compound

Procedure

By a procedure similar to that of example 1.85.3, starting from 2-benzoyl-5-chlorobenzothiophene, (Z)-ethyl 3-(5-chloro-2-benzothiophenyl)-3-phenylacrylate and (E)-ethyl 3-(5-chloro-2-benzothiophenyl)-3-phenylacrylate were obtained as yellowish oils.

Sources & evidence

ORD record
ord-ccceec0d67c542259b4741591f501e57
Source dataset
uspto-grants-2014_12
Patent number
US08912186B2

Reaction notes

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