HCID 66760116, compound → HCID 66759821, compound

Participants

Reaction Steps

The ester (135 mg) was dissolved in a mixture of acetic acid (2 ml) and conc. HCl (1 ml) and heated under reflux for 1 h. All volatiles are removed at the water aspirator and the residue was precipitated from acetone solution with ethyl acetate to give 3-(5-chloro-2-benzimidazolyl)-3-(4-chlorophenyl)propanoic acid HCl (130 mg) as colourless solid.

Provenance & Evidence