(2,4-Dichlorophenyl)acetyl chloride → HCID 66759482, compound
Reaction equation
[Cl:1][C:2]1[CH:7]=[C:6]([Cl:8])[CH:5]=[CH:4][C:3]=1[CH2:9][C:10](Cl)=[O:11].[C:13]1([NH:19][CH2:20][CH2:21][C:22]([O:24][CH2:25][CH3:26])=[O:23])[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1>>[Cl:1][C:2]1[CH:7]=[C:6]([Cl:8])[CH:5]=[CH:4][C:3]=1[CH2:9][C:10]([N:19]([CH2:20][CH2:21][C:22]([O:24][CH2:25][CH3:26])=[O:23])[C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1)=[O:11]Participants
3
Procedure
By a procedure similar to that of example 1.115.1, starting from 2,4-dichlorophenylacetyl chloride and ethyl N-phenyl-3-aminopropionate, ethyl 3-[2-(2,4-dichlorophenyl)-N-phenyl-acetamido]propanoate was obtained as yellowish oil.
Sources & evidence
- ORD record
- ord-5b6efb379efd40f5bfcafa0ee4d541a1
- Source dataset
- uspto-grants-2014_12
- Patent number
- US08912186B2
Reaction notes
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