4-Chlorophenylacetyl chloride → HCID 66759237, compound

HRID 1402935Notes

Reaction equation

HRID 1402935 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([CH2:8][C:9](Cl)=[O:10])=[CH:4][CH:3]=1.[Cl:12][C:13]1[CH:18]=[CH:17][C:16]([NH:19][CH2:20][CH2:21][C:22]([O:24][CH2:25][CH3:26])=[O:23])=[CH:15][CH:14]=1>>[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([CH2:8][C:9]([N:19]([CH2:20][CH2:21][C:22]([O:24][CH2:25][CH3:26])=[O:23])[C:16]2[CH:17]=[CH:18][C:13]([Cl:12])=[CH:14][CH:15]=2)=[O:10])=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 906924-Chlorophenylacetyl chlorideHCID 12646051HCID 12646051, compound

Product 1

HCID 66759237HCID 66759237, compound

Procedure

By a procedure similar to that of example 1.115.1, starting from 4-chlorophenylacetyl chloride and ethyl N-(4-chlorophenyl)-3-aminopropionate, ethyl 3-[2-(4-chloro-phenyl)-N-(4-chlorophenyl)acetamido]-propanoate was obtained as yellowish oil.

Sources & evidence

ORD record
ord-bbbf17ebdfa54851930732a2166b8932
Source dataset
uspto-grants-2014_12
Patent number
US08912186B2

Reaction notes

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