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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1402952Generated: October 30, 2026

Diethyl Malonate → Diethyl 2-(3-oxo-1-(4-phenylthiophen-2-yl)-3-(4-(trifluoromethyl)-phenyl)propyl)malonate

https://huagongshe.com/reaction/1402952

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDiethyl MalonateHCID 7761—
Reactant3-(4-Phenylthiophen-2-yl)-1-(4-(trifluoromethyl)phenyl)prop-2-en-1-oneHCID 66759394—
ProductDiethyl 2-(3-oxo-1-(4-phenylthiophen-2-yl)-3-(4-(trifluoromethyl)-phenyl)propyl)malonateHCID 66759432—

Reaction Steps

By a procedure similar to that of example 1.59.2, starting from 3-(4-phenylthiophen-2-yl)-1-(4-(trifluoromethyl)phenyl)prop-2-en-1-one and diethyl malonate, diethyl 2-(3-oxo-1-(4-phenylthiophen-2-yl)-3-(4-(trifluoromethyl)-phenyl)propyl)malonate was obtained as yellow oil.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08912186B2
Source datasetuspto-grants-2014_12
ORD IDord-9d38a48fd2294cf48325af8ef3f2c8dd
Source noteuspto-grants-2014_12