Barbituric Acid → HCID 66759496, compound

HRID 1402960Notes

Reaction equation

HRID 1402960 reaction equation
[O:1]([C:8]1[CH:13]=[CH:12][C:11]([C:14](=[O:23])[CH:15]=[CH:16][C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=2)=[CH:10][CH:9]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[NH:24]1[C:31](=[O:32])[CH2:30][C:28](=[O:29])[NH:27][C:25]1=[O:26]>>[O:23]=[C:14]([C:11]1[CH:12]=[CH:13][C:8]([O:1][C:2]2[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=2)=[CH:9][CH:10]=1)[CH2:15][CH:16]([CH:30]1[C:28](=[O:29])[NH:27][C:25](=[O:26])[NH:24][C:31]1=[O:32])[C:17]1[CH:18]=[CH:19][CH:20]=[CH:21][CH:22]=1

Participants

3

Reactant 2

HCID 6211Barbituric AcidHCID 238633HCID 238633, compound

Product 1

HCID 66759496HCID 66759496, compound

Procedure

By a procedure similar to that of example 1.59.2, starting from 1-(4-phenoxyphenyl)-3-phenylprop-2-en-1-one and barbituric acid, 5-(3-oxo-3-(4-phenoxyphenyl)-1-phenylpropyl)pyrimidine-2,4,6(1H,3H,5H)-trione was obtained as yellow solid.

Sources & evidence

ORD record
ord-60f2015803f24cd4970ca2f33c06ef89
Source dataset
uspto-grants-2014_12
Patent number
US08912186B2

Reaction notes

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