Dimethyl malonate → HCID 66760462, compound

HRID 1402963Notes

Reaction equation

HRID 1402963 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([CH:8]=[CH:9][C:10]([C:12]2[CH:17]=[CH:16][C:15]([O:18][CH2:19][O:20][CH3:21])=[CH:14][CH:13]=2)=[O:11])=[CH:4][CH:3]=1.[C:22]([O:29][CH3:30])(=[O:28])[CH2:23][C:24]([O:26][CH3:27])=[O:25]>>[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([CH:8]([CH:23]([C:22]([O:29][CH3:30])=[O:28])[C:24]([O:26][CH3:27])=[O:25])[CH2:9][C:10]([C:12]2[CH:13]=[CH:14][C:15]([O:18][CH2:19][O:20][CH3:21])=[CH:16][CH:17]=2)=[O:11])=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 7943Dimethyl malonateHCID 66760109HCID 66760109, compound

Product 1

HCID 66760462HCID 66760462, compound

Procedure

By a procedure similar to that of example 1.59.2, starting from 3-(4-chlorophenyl)-1-(4-methoxymethoxy-phenyl)prop-2-en-1-one and dimethyl malonate, dimethyl 2-(1-(4-chlorophenyl)-3-(4-(methoxymethoxy)phenyl)-3-oxopropyl)malonate was obtained as colourless solid.

Sources & evidence

ORD record
ord-9a85369f21984fd9bef3b2e0d4135276
Source dataset
uspto-grants-2014_12
Patent number
US08912186B2

Reaction notes

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