HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-tert-Butyl-5-isocyanato-1-p-tolyl-1H-pyrazole → 1-(3-tert-butyl-1-p-tolyl-1H-pyrazol-5-yl)-3-(3-(2-methyl-3-oxo-3,4-dihydropyrido[2,3-b]pyrazin-8-yloxy)phenyl)urea
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-tert-Butyl-5-isocyanato-1-p-tolyl-1H-pyrazole | HCID 17987855 | — |
| Reactant | 8-(3-aminophenoxy)-2-methylpyrido[2,3-b]pyrazin-3(4H)-one | HCID 46901594 | — |
| Product | 1-(3-tert-butyl-1-p-tolyl-1H-pyrazol-5-yl)-3-(3-(2-methyl-3-oxo-3,4-dihydropyrido[2,3-b]pyrazin-8-yloxy)phenyl)urea | HCID 46900427 | 57% |
Reaction Steps
Method F2 was used with 8-(3-aminophenoxy)-2-methylpyrido[2,3-b]pyrazin-3(4H)-one and 3-tert-butyl-5-isocyanato-1-p-tolyl-1H-pyrazole to afford the title compound as a white solid (89 mg, 57%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08912191B2 |
| Source dataset | uspto-grants-2014_12 |
| ORD ID | ord-97b66da20a7842029508fe1a0280ee5e |
| Source note | uspto-grants-2014_12 |