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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1403053Generated: October 31, 2026

3-tert-Butylbenzoyl chloride → 3-tert-butyl-N-(3-(3-oxo-3,4-dihydropyrido[2,3-b]pyrazin-8-yloxy)phenyl)benzamide

https://huagongshe.com/reaction/1403053

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-tert-Butylbenzoyl chlorideHCID 22143102—
Reactant8-(3-aminophenoxy)pyrido[2,3-b]pyrazin-3(4H)-oneHCID 46901593—
Product3-tert-butyl-N-(3-(3-oxo-3,4-dihydropyrido[2,3-b]pyrazin-8-yloxy)phenyl)benzamideHCID 4413372145%

Reaction Steps

Method G1 was used with 8-(3-aminophenoxy)pyrido[2,3-b]pyrazin-3(4H)-one and 3-tertbutylbenzoyl chloride to afford the title compound as a white solid (29 mg, 45%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08912191B2
Source datasetuspto-grants-2014_12
ORD IDord-d5a0eaba4bed41b9bb249326083e6352
Source noteuspto-grants-2014_12