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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1403054Generated: November 3, 2026

3-tert-Butylbenzoyl chloride → 3-tert-butyl-N-(3-(2-oxo-1,2-dihydropyrido[2,3-b]pyrazin-8-yloxy)phenyl)benzamide

https://huagongshe.com/reaction/1403054

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-tert-Butylbenzoyl chlorideHCID 22143102—
Reactant8-(3-aminophenoxy)pyrido[2,3-b]pyrazin-2(1H)-oneHCID 46899946—
Product3-tert-butyl-N-(3-(2-oxo-1,2-dihydropyrido[2,3-b]pyrazin-8-yloxy)phenyl)benzamideHCID 4413409022%

Reaction Steps

Method G1 was used with 8-(3-aminophenoxy)pyrido[2,3-b]pyrazin-2(1H)-one and 3-tertbutylbenzoyl chloride to afford the title compound as a white solid (14 mg, 22%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08912191B2
Source datasetuspto-grants-2014_12
ORD IDord-c8460319c11b4a85875fb0852c8e7f3d
Source noteuspto-grants-2014_12